The 5th International Conference on Frontiers in Computing and Systems (COMSYS-2024) will be held during December 13-15, 2024, at BITS Pilani, K. K. Birla Goa Campus, Goa, India to be jointly organized by the Department of Computer Science and Engineering, BITS Pilani Goa and COMSYS Educational Society, Kolkata, India. The main objective of COMSYS-2024 is going to present the latest research and results of scientists with a theme “Cyber-physical Systems for real-life applications” pertaining to Artificial Intelligence, Machine Learning & Data Science; Devices, Circuits and Systems; Computational Biology and Bioinformatics; Image, Video, and Signal Processing; Communication Networks, Cloud computing, Security, and IoT. This conference provides opportunities for delegates from different areas to exchange new ideas and application experiences face-to-face to establish academic or research collaborations. It will bring together researchers from academia and industry onto a common platform and help them to develop a comprehensive understanding of the challenges of technological advancements from different viewpoints. This conference will also help foster a healthy and vibrant relationship between academia and industry.